Fibromyalgia Research Links

Abnormal Pain Memory Helps To Explain Fibromyalgia (November 1, 2000) — The symptoms of fibromyalgia may be the result of a central nervous system that “remembers” pain sensations for an abnormally long time, according to research presented at the American College of Rheumatology Annual Scientific Meeting Oct. 29 — Nov. 2 in Philadelphia, Pennsylvania. > full story

Mayo Clinic Study Finds Brief Fibromyalgia Treatment Program Reduces Some Symptoms (April 10, 2001) — Mayo Clinic researchers have found that a brief interdisciplinary treatment program for fibromyalgia reduces some symptoms, especially in people more severely affected by this chronic disorder. > full story

Pain From Fibromyalgia Is Real, Researchers Say (November 28, 2006) — Many people with fibromyalgia — a debilitating pain syndrome that affects 2 to 4 percent of the population — have faced the question of whether the condition is real. Increasingly, though, the scientific knowledge about fibromyalgia is growing, and a new paper from the University of Michigan Health System says there are “overwhelming data” that the condition is real. > full story

Fibromyalgia Increases Pain And Fatigue For Pregnant Women (July 5, 2006) — Pregnant women with fibromyalgia (FM) experience significant pain, fatigue and psychological stress, symptoms that are often misdiagnosed or undertreated as a normal part of pregnancy, according to a pilot study by Karen M. Schaefer, D.N.Sc., R.N., assistant professor of nursing at Temple University’s College of Health Professions. Her research, the first to look at the impact of pregnancy on women with FM, was recently presented at the 2006 Association of Women’s Health, Obstetrics and Neonatal Nurses’ convention in Baltimore. > full story

High Risk Of Migraine, Depression And Chronic Pain For IBS Sufferers, Large Study Shows (September 28, 2006) — Patients with irritable bowel syndrome are more likely to suffer from conditions such as migraine or depression than other individuals. A study published today in BMC Gastroenterology shows that patients with irritable bowel syndrome are 60 percent more likely to suffer from depression, migraine or chronic pain than individuals who do not suffer from IBS. > full story

Fibromyalgia Patients May Benefit From Cough Remedy, UF Study Finds (May 19, 2005) — Dextromethorphan, an over-the-counter medication that silences coughs, may help fibromyalgia patients quiet over-reacting nerves that amplify ordinary touches into agony. > full story

Drug Used To Treat Parkinson’s Disease May Be Beneficial In Treating Fibromyalgia (July 28, 2005) — Recently, researchers set out to investigate whether the dopamine receptor agonist pramipexole was safe and effective in treating fibromyalgia. Normally used to treat Parkinson’s disease, this drug stimulates dopamine (a neurotransmitter) production by binding to dopamine receptor sites and is thought to inhibit sensory nerve-mediated responses. This is the first trial of pramipexole and only the second trial for this type of dopamine receptor agonist for the treatment of fibromyalgia. > full story

Brain Study Of Back Pain Sufferers Yields Intriguing Results; Scans Show Amplified Pain Signals In Patients With Back Pain Of Unknown Origin (October 28, 2002) — Patients with lower back pain that can’t be traced to a specific physical cause may have abnormal pain-processing pathways in their brains, according to a new study led by University of Michigan researchers. The effect, which as yet has no explanation, is similar to an altered pain perception effect in fibromyalgia patients recently reported by the same research team. > full story

Study Finds Fibromyalgia Prohibits Sufferers From Breast-feeding (September 23, 2004) — New mothers with fibromyalgia (FM) face multiple barriers to breast-feeding their babies, according to a study published recently in the American Journal of Maternal/Child Nursing. > full story

Baby Girls Born To Mothers Burdened By Stress May Be At Risk For Fibromyalgia (June 23, 2006) — Stressful or traumatic events experienced during pregnancy can have long-lasting effects on the fetus, yet these effects may not become apparent until many years later, according to a study suggesting that girls born of such pregnancies may be at greater risk for developing a painful muscle condition called fibromyalgia as adults. The study shows how vulnerable a fetus is to “prenatal programming.” > full story

Pain Research Using Electronic Diaries Helps Identify Who Responds To ‘Placebo Effect’ (November 23, 2005) — A new study by researchers at the University of Michigan Health System sheds some light on one group of people that seems to experience the ‘placebo effect.’ The researchers found that people with one type of chronic pain who have greater swings in their pain fluctuations tend to be more likely to respond to placebos. > full story

Sleep Disorders Often Indicate Multiple Health Conditions (November 5, 2004) — People who have difficulty sleeping at night or staying awake during the day may suffer from more than just a sleep disorder. According to a new study presented at CHEST 2004, the 70th annual international scientific assembly of the American College of Chest Physicians (ACCP), the majority of patients with obstructive sleep apnea (OSA) and/or nonrestorative sleep have a high degree of attention deficit, as well as neuromuscular and psychiatric conditions. > full story

Research Provides More Evidence That Chronic Fatigue Syndrome Is A Legitimate Medical Condition (January 10, 2006) — Researchers at Georgetown University Medical Center have found that chronic fatigue syndrome (CFS) may be rooted in distinct neurological abnormalities that can be medically tested. Although the sample studied was small, this research provides objective, physiological evidence that the controversial disorder can be considered a legitimate medical condition. > full story

Antidepressant Drug Tested In Treatment Of Bladder Disease (March 9, 2005) — Queen’s University has been selected as the only Canadian site to test a new antidepressant drug approved by the FDA (U.S. Food and Drug Administration) for its potential to alleviate pain in two common bladder conditions that have no known cause and no effective therapy. > full story

Evidence Of Estrogen And Progesterone Hormone Allergy Discovered (March 30, 2006) — Some women with menstrual cycle disorders like asthma and migraine headaches may be experiencing allergies to their own estrogen and progesterone hormones, Texas researchers have discovered. > full story

Genetic Mechanism Helps Explain Chronic Pain Disorders (December 27, 2006) — Researchers at the University of North Carolina at Chapel Hill have discovered that commonly occurring variations of a gene trigger a domino effect in chronic pain disorders. The finding might lead to more effective treatments for temporomandibular joint disorder (TMJD) and other chronic pain conditions. > full story

Mysterious Condition Still More Prevalent Among Persian Gulf Vets (January 6, 2006) — Comparing veterans deployed in the first Persian Gulf War and veterans deployed elsewhere at the same time has revealed veterans who served in the Persian Gulf have nearly twice the prevalence of chronic multi-symptom illness (CMI), a cluster of symptoms similar to a set of conditions often called Gulf War Syndrome. > full story

New Study Tests Amitriptyline For Painful Bladder Syndrome (February 23, 2005) — A new study will test an FDA-approved antidepressant for its potential to alleviate bladder pain for which there is no known cause and no effective therapy. Thousands, if not millions, of patients may benefit. The study is funded by the National Institutes of Health (NIH). > full story

Researchers Describe New Cost-effective Method To Assess Sleep (August 30, 2005) — Using information hidden in the beat-to-beat changes of the heart’s electrical signals, researchers at Beth Israel Deaconess Medical Center (BIDMC) have developed an inexpensive method to assess the stability and quality of sleep, which could be used to help understand the mechanisms of sleep control and diagnose sleep disorders, as well as to test the efficacy of sleep aids and other medications. > full story

Chronic Fatigue Patients Show Lower Response To Placebos (April 21, 2005) — Contrary to conventional wisdom, patients with chronic fatigue syndrome respond to placebos at a lower rate than people with many other illnesses, according to the first systematic review of the topic. > full story

Chronic Fatigue Patients Show Lower Response To Placebos (March 22, 2005) — Contrary to conventional wisdom, patients with chronic fatigue syndrome respond to placebos at a lower rate than people with many other illnesses, according to the first systematic review of the topic. > full story

Naked Mole-rats Bare Pain Relief Clues (November 17, 2003) — East African naked mole-rats, the only known cold-blooded mammal, have shown a rather heated response in lab tests that may have important implications for treating chronic pain in humans. > full story

Fatigue In Women Is Reduced In Stress-related Cortisol Study (November 14, 2006) — A study of healthy women has harvested results involving fatigue and vigor that eventually may help researchers fine tune efforts to treat a multitude of illnesses and syndromes linked to low levels of the stress hormone cortisol. > full story

Immunotherapy Treatment Shows Dramatic Results For Rare Neurological Disorder (December 28, 2001) — An immunologic therapy, intravenous immunoglobulin (IVIg), administered to patients suffering from stiff person syndrome (SPS), provides dramatic relief from disabling symptoms, according to a study appearing in the December 27, 2001, issue of The New England Journal of Medicine.* The study’s principal author, Marinos C. Dalakas, M.D., chief of the Neuromuscular Diseases Section of the National Institute of Neurological Disorders and Stroke, says that the success of the treatment supports the theory that SPS is the result of an autoimmune response gone awry in the brain and spinal cord. > full story

Scientists Discover Genetic Basis For Individual Variations In Pain Perception And A Common Chronic Pain Condition (January 12, 2005) — An age-old question is why some people seem to be able to withstand high levels of discomfort while comparable pain causes others to cry for mercy. A related question is how some people can live through major physical and psychological stresses with no apparent consequences while others develop chronic pain conditions. Now, University of North Carolina at Chapel Hill scientists, collaborating with National Institutes of Health, the University of Adelaide and Attagene Inc. researchers, say they have discovered a major part of the answers to both questions. > full story

Gender And Sex Hormones Affect The Brain’s Pain Response And More, According To New Studies (November 1, 2004) — Scientists are now uncovering increasing evidence that the brain not only responds to hormones produced by the reproductive system, but that these hormones—the so-called “female hormones,” estrogen and progestin, and the “male” androgens, such as testosterone—play an important role in the development of differences between male and female brains. > full story

Scientists At Princess Margaret Hospital And Amgen Discover Role Of T Cells In Bone Destruction (November 18, 1999) — The role of T cells in the crippling bone and cartilage deterioration characteristic of many diseases including arthritis and other inflammatory diseases has been unraveled for the first time by a research team at Princess Margaret Hospital and the AMGEN Research Institute. Inflammation can trigger the body’s T cells to inadvertently cannibalize its own bone, leading to severe bone degeneration and debilitating pain. > full story

Narcotic Drugs Effective For Severe, Chronic Pain In Older Patients (May 20, 2005) — Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, UCSF medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences. > full story

Teaching The Art Of Aromatherapy To Soothe And Heal (August 25, 2006) — A bubble bath that improves memory. A kitchen cleaner that wards off nausea and energizes. A scented handkerchief that calms a patient entering the MRI. The benefits of aromatherapy are real. Learn the uses, healing properties and how-tos of using aromatherapy to heal and de-stress from the University of Texas M. D. Anderson Cancer Center in Houston. > full story